The Canadian Committee on Antibiotic Resistance

February 2, 2007 - CIPARS 2005 Preliminary Results Released

The Canadian Integrated Program for Antimicrobial Resistance Surveillance (CIPARS) preliminary results are now available:

CIPARS 2005 Preliminary Results (PDF format)

In addition, PHAC has also released additional data, including the frequency of bacterial isolation (recovery rates) for various commodities and products in their active surveillance programs from 2002 to 2005:

Recovery rate and final number of isolates submitted for antimicrobial resistance (AMR) testing across the bacterial species, the active surveillance components and the animal species, 2002-2005 (PDF format).

For additional information, please visit the CIPARS website.

2003 Report from the Canadian Integrated Program on Antimicrobial Resistance Surveillance (CIPARS)

Groupe Contre la Résistance Antimicrobiens (GRAM) sl

ide presentation on antibiotic resistance in Quebec 1995 - 2000. Weiss, K. November 28, 2001. (Microsoft PowerPoint Document)

Respiratory pathogens susceptibility to antibiotics in Quebec: 2000-2001. (Microsoft PowerPoint Document)

Dr. Andy Simor. Presentation on Antibiotic Resistance in Canada. 3M Seminar, November 4, 2001. (Microsoft PowerPoint document)

National Workshop on Antimicrobial Resistance - Meeting Minutes - March 2000 for copies of the document, send e-mail request to:

Quebec Provincial Surveillance Program for Streptococcus pneumoniae, Haemophilus influenzae et Moraxella catarrhalis. Data provided by the Groupe contre la Résistance aux Anti-Microbiens. (Microsoft PowerPoint format in French only)

Health Canada - Laboratory Centre for Disease Control

Canadian Journal of Infectious Diseases Home Page

Canadian Journal of Infectious Diseases- Search for Abstracts

CHICA (Community and Hospital Infection Control Association- Canada)

Antimicrobial Resistance Surveillance in Agri-Food and Aquaculture

Surveillance of Antimicrobial Use in Animals: Canadian Pilot Projects

Canadian Bacterial Diseases Network

March 29, 2007 - Report from Sweden on antibiotic utilisation and resistance
"Swedres 2005", the fifth report on Swedish antibiotic utilisation and resistance in human medicine, was presented in May 2006. Compared with the rest of Europe, antibiotic consumption and resistance levels in Sweden are relatively low. However, global travel and trade facilitate the spread of bacteria between countries and continents. As a consequence, also in Sweden, increasing resistance trends are seen for some pathogens, notably ESBL-producing enterobacteriaceae.

Smittskyddsinstutet (Swedish Institute for Infectious Disease Control), Stolckholm, Sweden

CDC - Emerging Infectious Diseases Advanced Search

Centers for Disease Control- Antimicrobial Resistance

World Health Organization- Surveillance

EuroSurveillance - links to weekly and monthly publications

Please note that more links are available in the OVERVIEW -> International section

Vancomycin-resistant Enterococcus (VRE)

Low Prevalence of Vancomycin-resistant Enterococci Gastrointestinal Colonization of Hospitalized Patients in Manitoba Tertiary Care and Community Hospitals. Zhanel et al. Canadian Journal of Infectious Diseases. Vol 11 No. 1. January/February 2000.
The Emerging Epidemiology of Vancomycin-resistant Enterococci in Canada 1993-98: Results from the Canadian Nosocomial Infection Surveillance Program (CNISP) Passive Reporting Network (PRN). Conly et al. The Canadian Journal of Infectious Diseases. Vol. 10 Supplement D. September/October 1999.
Emerging Epidemiology of Vancomycin-resistant Enterococci in Canada. Conly & Shafran. The Canadian Journal of Infectious Diseases. Vol. 8 No. 4. July/August 1997.
Vancomycin-resistant Enterococci (VRE) in Canada - Results of the Canadian Nosocomial Infection Surveillance Program 1996 VRE Point Prevalence Surveillance Project. Ofner-Agostini et al. The Canadian Journal of Infectious Diseases. Vol. 8 No. 2. March/April 1997.

Methicillin-resistant Staphylococcus aureus (MRSA)
(See below for the Community-Acquired MRSA)

National Post reports front page story on MRSA based on Canadian Communicable Disease Report. Surveillance for Methicillin-Resistant Staphylococcus aureus in Canadian Hospitals - A Report Update from the Canadian Nosocomial Infection Surveillance Program
Canadian Nosocomial Infection Surveillance Program MRSA Statistics to June 2002. (Microsoft PowerPoint document)
The Economic Impact of Methicillin-Resistant Staphylococcus Aureus in Canadian Hospitals. T. Kim, P. Oh, A. Simor. Infection Control and Hospital Epidemiology. Feb 2001. Vol 22 (7).
CNISP MRSA Surveillance Study. CCDR Vol 23-6, 15 March 1997 - April 2000
CNISP study on MRSA - An Integrated Approach to Communicable Disease Surveillance April 2000
Characterization and proposed nomenclature of epidemic strains of MRSA in Canada. Simor et al. Canadian Journal of Infectious Diseases. Vol. 10 No. 5. September/October 1999.
CHEC/CNISP surveillance data on MRSA and VRE, presented at the CHICA-Canada meeting by A. Simor, May, 2000. (Microsoft PowerPoint document)

Community Acquired MRSA

Strategies for Clinical Management of MRSA in the Community: Summary of an Experts Meeting Convened by the Centers for Disease Control and Prevention (Adobe Acrobat Document)
Epidemic Community-Associated Methicillin-Resistant Staphylococcus aureus. Modern Times for an Ancient Pathogen (Adobe Acrobat Document)
Treatment of Community-Associated Methicillin-Resistant Staphylococcus aureus Infections (Adobe Acrobat Document)
Severe Staphylococcal Sepsis in Adolescents in the Era of Community-Acquired Methicillin-Resistant Staphylococcus aureus (Adobe Acrobat Document)
Three-Year Surveillance of Community-Acquired Staphylococcus aureus Infections in Children (Adobe Acrobat Document)
Careful Use of Antibiotics in Washington State - Methicillin Resistant Staphylococcus Aureus Guidelines MRSA Health Care Provider Information
Information on community-acquired MRSA made available from the Mayo Clinic. October 2005 (Adobe Acrobat Document)
Community-acquired MRSA is on the rise in Canada. A workshop on the issue will be held in Toronto on October 27 & 28, 2005. Current publications with more details on the problem are now available.
- Molecular Epidemiology of Community- and Health Care-Associated Methicillin-Resistant Staphylococcus aureus in Manitoba, Canada
- Community-associated Methicillin-resistant Staphylococcus aureus, Canada

Penicillin-resistant Streptococcus pneumoniae (PRSP)

Streptococcus pneumoniae and Antibiotics Resistance. The EQUERE Project - Quebec 1998-2004 (Microsoft PowerPoint document)
New information on Streptococcus pneumoniae from the Canadian Bacterial Diseases Network. (Microsoft PowerPoint document)
Update on Penicillin Resistance Rates Among Pneumonococci Causing Invasive Infection in Children - Canada. Scheifele et al. Presented at the CPS Annual Meeting, Ottawa, June 15, 2000
Phenotypic and Genotypic Characterization of Macrolide-Resistant Group A Streptococcus Strains in the Province of Quebec. K Weiss et al. Journal of Antimicrobial Chemotherapy. March 2001. Vol 47: 345-348
Decreased Susceptibility of Streptococcus pneumoniae to Floroquinolones in Canada. Chen et al. New England Journal of Medicine. Vol. 341:233-239. July 22, 1999.
Preventing Pneumococcal Disease: A Canadian Consensus Conference - February 16-18, 1998. The Canadian Journal of Infectious Diseases. Vol. 10 Supplement A. January/February 1999.
Invasive Pneumococcal Disease in Canada 1996: Results from Sentinel Health Unit Surveillance System. Kertesz et al. The Canadian Journal of Infectious Diseases. Vol. 10 Supplement A. January/February 1999.
Antimicrobial-Resistant Streptococcus pneumoniae. Lovgren and Talbot. The Canadian Journal of Infectious Diseases. Vol.10. Supplement A. January/February 1999.
A Cross-Canada Surveillance of Antimicrobial Resistance in Respiratory Tract Pathogens. Davidson et al. Canadian Journal of Infectious Diseases. Vol 10. No 2. 1999.
Antibiotic-resistant Streptococcus pneumoniae - Implications for Medical Practice. Wang, Kellner and Arnold. Canadian Family Physician. Vol 44. September 1998.
Penicillin Resistance Among Invasive Pneumococcal Isolates at 10 Children's Hospitals, 1991-1994
Health Canada - Invasive Meningococcal Disease and Antibiotic Resistant Streptococcus pneunoniae
Power Point Presentation on Streptococcus pneumoniae from the Canadian Bacterial Diseases Network. January 2002.
Susceptibility of Group A Beta-hemolytic Streptococci in the Lower St Lawrence Region, Quebec, Canada. DesRosiers et al. Canadian Journal of Infectious Diseases. Vol 10. No 4. 1999.

Haemophilus influenzae

Antibiotic Resistance in Respiratory Tract Isolates of Haemophilus influenzae and Moraxella catarrhalis Collected from Across Canada. Zhanel et al. Journal of Antimicrobial Chemotherapy. Vol. 45. No. 5. May 2000.
A Cross-Canada Surveillance of Antimicrobial Resistance in Respiratory Tract Pathogens. Davidson et al. Canadian Journal of Infectious Diseases. Vol 10. No 2. 1999.
Haemophilus influenzae type b (Hib)- Canada Communicable Disease Report - Volume 24-13, July 1, 1998

Salmonella

National Laboratory Surveillance of Enteric Pathogens. Ng et al. The Canadian Journal of Infectious Diseases. Vol. 8 No. 3. May/June 1997

Extended Spectrum Beta-lactamases (ESBLs) and Gram-negative Bacilli

An outbreak of extended spectrum beta-lactamase (esbl) producing, multi-drug resistant (mdr) E. coli in long term care facilities. Muller MP, McGeer A, et al.Abstract I2, Conjoint Meeting of CACMID, CHICA & CIDS,Victoria,British Columbia, 4-8 November, 2001.
Guidelines on Susceptibility Testing of Antibiotic-Resistant Enterobacteriaceae due to Extended Spectrum Beta-Lactamases (ESBLs)
Survey of Bloodstream Infections Due to Gram-negative Bacteria: Frequency of Occurrence and Antimicrobial Susceptibility of Isolates Collected in the US, Canada and Latin America for the SENTRY Antimicrobial Surveillance Program, 1997. Diekema et al. Clinical Infectious Diseases. 1999:29:595-607
Extended Spectrum Beta-lactam Resistant Enterobacteriaceae: The Nosocomial Pathogen du Jour? Where Does the List End? Gardam and Conly. Canadian Journal of Infectious Diseases. Vol 10. No 6. 1999.
Cross-Canada Survey of Resistance of 2747 Aerobic Blood Culture Isolates to Piperacillin/Tazobactam and Other Antibiotics. Forward et al. Canadian Journal of Infectious Dieseases. Vol 9. No 1. 1998.
Study of the Comparative Activity of Piperacillin/Tazobactam with Currently Available Antibiotics Against 8206 Aerobic Isolates. Forward et al. Canadian Journal of Infectious Diseases. Vol 8. No 3. 1997
Incidence and Susceptibility of Aerobic Gram-negative Bacilli From 20 Canadian Intensive Care Units: 1989-1993. Bryce et al. Canadian Journal of Infectious Diseases. Vol 7. No. 1. 1997.

Multi Drug Resistant Tuberculosis (MDR TB)

Navigating the World Wide Web in Search of Resources on Antimicrobial Resistance (Adobe Acrobat Document)

Infectious Disease Outbreaks in Competitive Sports (Adobe Acrobat Document)

Community-Acquired MRSA Skin/Soft Tissue Infection Rates Increasing (Microsoft Word document)

Other

CCAR released a report which provides a snapshot of Canadian capability for surveillance of antimicrobial resistant organisms and provides an assessment of the international programs that Canada may wish to emulate.
CCAR is soliciting comments on the report which we recently commissioned entitled: Toward an International Report on Antimicrobial Resistance. Comments should be sent to by February 28, 2006. (Adobe Acrobat Document)
NIPA releases National Report Card on Antibiotic Resistance
Commends efforts but sounds warning. (Microsoft Word Document)
Health Canada Report on Nationwide Surveillance of AMR. (Microsoft Word document)
Antimicrobial Resistance: A Deadly Burden No Country Can Afford to Ignore. Birnbaum, Twells. March 2002. (Microsoft Word document)
Markov Model Data Set. (Microsoft Excel Spreadsheet)
Establishing Priorities for National Communicable Disease Surveillance. Doherty. Canadian Journal of Infectious Diseases. Vol 11 No. 1. January/February 2000.